A2780 ovarian cells neither catalysed drugmetabolism nor contained these drug transporters.
2
During the inflammatory response, intrahepatic cholestasis and decreased drugmetabolism are frequently observed.
3
CCRP appears to be involved in various hepatic regulations far beyond CAR-mediated drugmetabolism.
4
Expression data were compared to changes in conventional clinical chemistry parameters and drugmetabolism activities.
5
Genetic variation in genes encoding cytochrome P450 enzymes has important clinical implications for drugmetabolism.
Ús de xenobiotic metabolism en anglès
1
The contribution of cytosolic enzymes to xenobioticmetabolism may be remarkable in extrahepatic tissues.
2
Mothers and children shared variation in xenobioticmetabolism genes.
3
The enzyme was unable to hydrolyze 4-nitrophenyl sulfate, suggesting its role in xenobioticmetabolism does not extend beyond phosphates.
4
One important class of biological reactive intermediates arising in the course of human xenobioticmetabolism are arene and alkene oxides.
5
In addition, a new study reveals the mutual repression between PXR and NF-kappaB signaling pathways, providing a molecular mechanism linking xenobioticmetabolism and inflammation.
6
Those results reinforce the important role of gills in xenobioticmetabolism and suggest the involvement of the mentioned genes in the detoxification of the compound.
7
Xenobioticmetabolism can induce the generation of protein radicals, which are believed to play an important role in the toxicity of chemicals and drugs.